1,4-Dioxane hydrochloride → HCID 68583989, compound

HRID 1951854Notes

Reaction equation

HRID 1951854 reaction equation
C(OC(=O)[NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([C:14]2[S:18](=[O:20])(=[O:19])[N:17]([C:21]([CH3:24])([CH3:23])[CH3:22])[C:16](=[O:25])[CH:15]=2)[CH:9]=1)(C)(C)C.Cl.O1CCOCC1>>[NH2:7][C:8]1[CH:9]=[C:10]([C:14]2[S:18](=[O:20])(=[O:19])[N:17]([C:21]([CH3:23])([CH3:22])[CH3:24])[C:16](=[O:25])[CH:15]=2)[CH:11]=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 204431481,4-Dioxane hydrochlorideHCID 68583264HCID 68583264, compound

Product 1

HCID 68583989HCID 68583989, compound

Procedure

[3-(2-tert-Butyl-1,1,3-trioxo-2,3-dihydro-1H-isothiazol-5-yl)-phenyl]-carbamic acid tert-butylester (77 mg, 0.20 mmol) was treated with 1,4-dioxane-HCl following general procedure V to give 5-(3-Amino-phenyl)-2-tert-butyl-isothiazol-3-one-1,1-dioxide.

Sources & evidence

ORD record
ord-ddcd559ad4974e34981807b06d7ba70f
Source dataset
uspto-grants-2013_03
Patent number
US08404731B2

Reaction notes

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