Sodium Acetate → HCID 68554691, compound

Participants

Reaction Steps

Heated the reaction mixture of 250 grams of 2-((4R,6S)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxan-4-yl)-N,N-diisopropylacetamide, 225 grams of sodium acetate and 290 grams of tetra butyl ammonium bromide to 110-115° C. Stirred the reaction for 12 hours at 110-115° C. Diluted the reaction mixture with petroleum ether and filtered the byproduct. Organic layer washed with water. Distilled the solvent completely under reduced pressure. Isolated the material in petroleum ether. Dried the material at 40-45° C. to get the title compound.

Provenance & Evidence