HCID 57595758, compound → HCID 59593323, compound

HRID 1952018Notes

Reaction equation

HRID 1952018 reaction equation
C(NC1N=CC(C(C2C3C(=NC=CC=3)NC=2)=O)=CC=1)C(C)C.[CH:23]1([CH2:29][NH:30][C:31]2[N:36]=[CH:35][C:34]([C:37]([C:39]3[C:47]4[C:42](=[N:43][CH:44]=[CH:45][CH:46]=4)[NH:41][CH:40]=3)=O)=[CH:33][CH:32]=2)[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1>>[CH:23]1([CH2:29][NH:30][C:31]2[CH:32]=[CH:33][C:34]([CH2:37][C:39]3[C:47]4[C:42](=[N:43][CH:44]=[CH:45][CH:46]=4)[NH:41][CH:40]=3)=[CH:35][N:36]=2)[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1

Participants

3

Reactant 2

HCID 57595758HCID 57595758, compoundHCID 59593368HCID 59593368, compound

Product 1

HCID 59593323HCID 59593323, compound

Procedure

was prepared following the protocol of Scheme 8, substituting (6-Isobutylamino-pyridin-3-yl)-(1H-pyrrolo[2,3-b]pyridin-3-yl)-methanone P-0025 with [6-(Cyclohexylmethyl-amino)-pyridin-3-yl]-(1H-pyrrolo[2,3-b]pyridin-3-yl)-methanone P-0031, (prepared as described in Example 5). MS (ESI) [M+H+]+=321.

Workup

  1. customwas prepared

Sources & evidence

ORD record
ord-f0214b34e5c24f05ab8a0ef384fc54ab
Source dataset
uspto-grants-2013_03
Patent number
US08404700B2

Reaction notes

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