Acetic Anhydride → 3,5-Dioxohexanoic acid

Participants

Reaction Steps

To methyl 2-azido-2-deoxy-1-thio-β-D-glucopyranoside. (10 g, 42.50 mmol) in pyridine (50 mL) at 0° C. was added acetic anhydride (20 g) and the reaction stirred for 1 hour. The reaction mixture was evaporated to dryness and the residue extracted to give the title triacetate (15.23 g, quantitative), Rf=0.7 (CHCl3/Petroleum ethers, 1:1).

Provenance & Evidence