化工社化工社 化学情報印刷レポート · 研究参考用
thiirane (E)-ethyl 7-(thiiran-2-yl)hept-6-enoate → Ethyl 5-(2,5-dihydrothiophen-2-yl)pentanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | thiirane (E)-ethyl 7-(thiiran-2-yl)hept-6-enoate | HCID 86630496 | — |
| 溶媒 | Benzene | HCID 241 | — |
| 生成物 | Ethyl 5-(2,5-dihydrothiophen-2-yl)pentanoate | HCID 16070980 | 80% |
反応手順
A solution of thiirane (E)-ethyl 7-(thiiran-2-yl)hept-6-enoate (40 mg, 0.19 mmol) and Cu(hfacac)2 (4.7 mg, 10 μmol) in benzene (20 mL) was heated at 120° C. for 1.5 h in a pressure tube. Concentration of the solvent in vacuo afforded a residue, which was purified by column chromatography (n-pentane) to give Ethyl 5-(2,5-dihydrothiophen-2-yl)pentanoate (32 mg, 80%) as a colorless oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08404872B2 |
| 出典データセット | uspto-grants-2013_03 |
| ORD ID | ord-389dec8c884e495fa9090ffecdf6d2af |
| 出典メモ | uspto-grants-2013_03 |