HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl 3-(bromomethyl)-6-fluoro-1H-pyrazolo[3,4-b]pyridine-1-carboxylate → HCID 178505430, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl 3-(bromomethyl)-6-fluoro-1H-pyrazolo[3,4-b]pyridine-1-carboxylate | HCID 25132591 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 178505430 | HCID 178505430 | 100.2% |
Reaction Steps
A solution of 1-Boc-3-(bromomethyl)-6-fluoro-1H-pyrazolo[3,4-b]pyridine (2-1; 195 mg; 0.59 mmol) was stirred in TFA (1 mL) for approximately 30 minutes. The reaction was concentrated in vacuo to give 136 mg (99%) of the desired product as a yellow solid after pumping. The crude product was used as is in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404856B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-77bd2215d4334a35a85dee570fad03be |
| Source note | uspto-grants-2013_03 |