HCID 86664858, compound → HCID 86664857, compound

Participants

Reaction Steps

To a stirred solution of 9 (0.07 g, 0.06 mmol) in EtOAc (20 mL) was added dry powdered 10% Pd—C (0.007 g). The resulting mixture was stirred at room temperature for 48 hours under H2 balloon. Pd—C was filtered off and the filtrate was concentrated to give 10 as colorless oil (0.07 g, 80%). The crude product was subjected to the next reaction without further purification. 1H NMR (CDCl3) δ 7.78-7.80 (m, 6H), 7.65-7.69 (m, 7H), 7.14-7.33 (m, 14H), 6.76 (d, J=7.2 Hz, 1H), 6.61 (s, 1H), 5.52 (s, 2H), 4.05 (q, J=6.8 Hz, 2H), 3.62-3.67 (m, 8H), 2.62 (m, 2H), 2.45-2.54 (m, 8H), 2.19-2.22 (m, 2H), 1.56-1.67 (m, 12H), and 1.22-1.35 (m, 17H),

Provenance & Evidence