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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1952591Generated: November 2, 2026

Trifluoroacetic acid → HCID 68226607, compound

https://huagongshe.com/reaction/1952591

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 68226458HCID 68226458—
SolventDichloromethaneHCID 6344—
ProductHCID 68226607HCID 68226607—

Reaction Steps

To a solution of (S)-3-tert-Butoxycarbonylamino-2-{[5-(3-hydroxy-benzylcarbamoyl)-3-phenyl-thiophene-2-carbonyl]-amino}-propionic acid methyl ester (0.148 g, 0.27 mmol) in DCM (5 mL) was added TFA (2.0 mL). The mixture was stirred at room temperature 1 h and evaporated. Isolate 0.23 g of crude product which was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08404859B2
Source datasetuspto-grants-2013_03
ORD IDord-34d0b1d26f2447c5bf1de6b8a89f5c53
Source noteuspto-grants-2013_03