Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Fumaric Acid → (1RS,8RS,9RS)-7-Bicyclo[6.2.0]dec-9-yl-1-phenyl-1,7-diaza-spiro[3.5]nonan-2-one fumarate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Fumaric Acid | HCID 444972 | — |
| 반응물 | 1-Phenyl-1,7-diazaspiro[3.5]nonan-2-one | HCID 10976874 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | (1RS,8RS,9RS)-7-Bicyclo[6.2.0]dec-9-yl-1-phenyl-1,7-diaza-spiro[3.5]nonan-2-one fumarate | HCID 23298907 | — |
반응 단계
Reaction of (1RS,8RS)-bicyclo[6.2.0]dec-9-one and 1-phenyl-1,7-diaza-spiro[3.5]nonan-2-one in accordance with the general method of example 1 and treatment of the base with fumaric acid in diethyl ether yielded the title compound, pale brown solid, m.p. 158° C. and MS: m/e=353.4 (M+H+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06113527 |
| 출처 데이터셋 | uspto-grants-2000_09 |
| ORD ID | ord-12f50d4331a249b9b52f50750c5ba5a4 |
| 출처 메모 | uspto-grants-2000_09 |