Thionyl Chloride → HCID 23300100, compound

HRID 1952789Notes

Reaction equation

HRID 1952789 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[NH:8][C:7](=[O:12])[C:6]([CH3:13])=[C:5]2[C:14]([OH:16])=O.S(Cl)([Cl:19])=O>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[NH:8][C:7](=[O:12])[C:6]([CH3:13])=[C:5]2[C:14]([Cl:19])=[O:16]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 15389085HCID 15389085, compound

Product 1

HCID 23300100HCID 23300100, compound

Procedure

6.5 g (0.027 mol) of the carboxylic acid prepared in Example 1 are dissolved in 80 ml of thionyl chloride and heated under reflux for two hours. For working-up, the reaction mixture is concentrated under reduced pressure on a rotary evaporator and the residue which remains is stirred with diethyl ether. The reaction product is filtered off and the solid obtained is dried in vacuo.

Workup

  1. temperatureheated
  2. temperatureunder reflux for two hours
  3. concentrationthe reaction mixture is concentrated under reduced pressure on a rotary evaporator
  4. filtrationThe reaction product is filtered off
  5. customthe solid obtained
  6. customis dried in vacuo

Sources & evidence

ORD record
ord-929bb7a3fc184b19a8c2bd7b05e34e72
Source dataset
uspto-grants-2000_09
Patent number
US06114349

Reaction notes

Loading…