Glycine tert-butyl ester → HCID 23301391, compound

HRID 1952836Notes

Reaction equation

HRID 1952836 reaction equation
[C:1]([CH:9]1[CH:14]([C:15](=O)[C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH2:13][CH:12]=[CH:11][CH2:10]1)(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:23][CH2:24][C:25]([O:27][C:28]([CH3:31])([CH3:30])[CH3:29])=[O:26]>C(O)(=O)C>[C:2]1([C:1]2[N:23]([CH2:24][C:25]([O:27][C:28]([CH3:31])([CH3:30])[CH3:29])=[O:26])[C:15]([C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=3)=[C:14]3[C:9]=2[CH2:10][CH:11]=[CH:12][CH2:13]3)[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 151417Glycine tert-butyl esterHCID 232009MLS002639255

Product 1

HCID 23301391HCID 23301391, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

The procedure is as in Example 6, using as substrate 4,5-dibenzoylcyclohexene (Preparation 2) and as the reagent tert-butyl 2-aminoacetate in the presence of acetic acid.

Sources & evidence

ORD record
ord-3f553c702a744a3288c6a3a56b688028
Source dataset
uspto-grants-2000_09
Patent number
US06114360

Reaction notes

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