Acetone → HCID 70257737, compound

Participants

Reaction Steps

A solution of trans-2,3-bis(acetoxymethyl)-cyclopentanone [Compound (a)] (205 mg, 0.899 mmol) in acetone (7.2 ml) was added to N-acetyl-L-cysteine (147 mg, 0.899 mmol), and then added IN-sodium hydroxide (1.8 ml), stirred at room temperature for 15 minutes. The reaction solution was concentrated. The residue was purified by Sephadex LH-20 (11.80% aqueous methanol) to obtain the compound (II) (276 mg, yield 86.9%).

Provenance & Evidence