HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → ethyl 4,4-diethoxypentanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Ethyl levulinate | HCID 10883 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Catalyst | p-Toluenesulfonic acid | HCID 6101 | — |
| Product | ethyl 4,4-diethoxypentanoate | HCID 523027 | 72.5% |
Reaction Steps
A mixture of 171.3 g (1.19 mol) of ethyl 4-oxopentanoate, 207 ml (184.2 g, 1.24 mol) of triethyl orthoformate, 26 ml of absolute ethanol and 1 g of p-toluenesulfonic acid was refluxed for 8 h with vigorous stirring and then distilled under reduced pressure. 187.9 g (72.5%) of ethyl 4,4-diethoxypentanoate were obtained, boiling point 104-106° C./14 mm Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06114358 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-64bd6f0af8974541a784a1c7f5d0b1e0 |
| Source note | uspto-grants-2000_09 |