5-formyl-1-methyl-1H-pyrrole-3-carbonitrile → 5-(aminomethyl)-1-methyl-1H-pyrrole-3-carbonitrile

HRID 1952862Notes

Reaction equation

HRID 1952862 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([CH:9]=O)[N:6]([CH3:8])[CH:7]=1)#[N:2].[NH2:11]CC1N(C)C(C#N)=CC=1>>[NH2:11][CH2:9][C:5]1[N:6]([CH3:8])[CH:7]=[C:3]([C:1]#[N:2])[CH:4]=1

Participants

3

Reactant 2

HCID 127304775-formyl-1-methyl-1H-pyrrole-3-carbonitrileHCID 225600125-(Aminomethyl)-1-methyl-1H-pyrrole-2-carbonitrile

Product 1

HCID 227160185-(aminomethyl)-1-methyl-1H-pyrrole-3-carbonitrile

Procedure

5-Aminomethyl-1-methylpyrrole-3-carbonitrile were prepared starting from 4-cyano-1-methylpyrrole-2-carbaldehyde similar to the synthesis of 5-aminomethyl-1-methylpyrrole-2-carbonitrile.

Sources & evidence

ORD record
ord-66868fabd2ec44d7a58f9c7807ae77dd
Source dataset
uspto-grants-2000_09
Patent number
US06114358

Reaction notes

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