HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 11323531, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Anisole | HCID 7519 | — |
| Reactant | HCID 9929892 | HCID 9929892 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 11323531 | HCID 11323531 | — |
Reaction Steps
Trifluoroacetic acid (168 ml) was added to a solution of tert-butyl 4-{2-[(5-isopropyl-1,3-thiazol-2-yl)amino]-2-oxoethyl)-1,3-thiazol-2-ylcarbamate (22 g, 57.51 mmol) in CH2Cl2 (750 ml) and anisole (9.33 ml, 86.27 mmol) under ice-cooling.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06114365 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-3f630b7915a94c8ca1f55a7875a99127 |
| Source note | uspto-grants-2000_09 |