HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1952911Generated: November 4, 2026
Methyl 2-(2-nitro-4-(trifluoromethyl)phenyl)acetate → 6-Trifluoromethyloxindole
https://huagongshe.com/reaction/1952911
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl 2-(2-nitro-4-(trifluoromethyl)phenyl)acetate | HCID 83569 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 6-Trifluoromethyloxindole | HCID 608487 | — |
Reaction Steps
Methyl 2-nitro-4-trifluoromethylphenylacetate (26 mg) was hydrogenated over 10% palladium on carbon and then heated at 100° C. for 3 hours. The catalyst was removed by filtration and the solvent evaporated to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06114371 |
|---|
| Source dataset | uspto-grants-2000_09 |
|---|
| ORD ID | ord-36467113cb224f729638d1016aad16f4 |
|---|
| Source note | uspto-grants-2000_09 |
|---|
