HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-(4-Methylphenyl)propanoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-(p-Tolyl)propionic acid | HCID 73927 | — |
| Product | 3-(4-Methylphenyl)propanoyl chloride | HCID 13029200 | — |
Reaction Steps
3-(4-Methylphenyl)propanoic acid (0.055 moles, 9 g) is dissolved in thionyl chloride (1.008 moles, 120 g). The mixture is stirred for 30' at r.t., then refluxed for 1 h 30', evaporated under vacuum to an oil and taken up with toluene and hexane, each time evaporating to dryness. Yield: 12.4 g
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06114391 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-5de4e56af3a045cf87d8bd2bb6419edf |
| Source note | uspto-grants-2000_09 |