Benzoyl chloride → 4-(Benzoylamino)benzeneacetic acid

HRID 1952993Notes

Reaction equation

HRID 1952993 reaction equation
[C:1](Cl)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:10][C:11]1[CH:16]=[CH:15][C:14]([CH2:17][C:18]([OH:20])=[O:19])=[CH:13][CH:12]=1>C(O)C>[C:1]([NH:10][C:11]1[CH:12]=[CH:13][C:14]([CH2:17][C:18]([OH:20])=[O:19])=[CH:15][CH:16]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 7412Benzoyl chlorideHCID 145334-Aminophenylacetic acid

Product 1

HCID 51740564-(Benzoylamino)benzeneacetic acidYield 52%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 4a) from benzoylchloride and 4-aminobenzene acetic acid in a yield of 52% of theory. Colourless crystals, Mp. 207-208° C. (ethanol).

Sources & evidence

ORD record
ord-1dad895073434958b8b4cdf9f1ed7a75
Source dataset
uspto-grants-2000_09
Patent number
US06114390

Reaction notes

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