2-Naphthoyl chloride → HCID 136333692, compound

HRID 1953012Notes

Reaction equation

HRID 1953012 reaction equation
[NH2:1][C:2](=[N:12][N+:13]([O-:15])=[O:14])[NH:3][CH2:4][CH2:5][CH2:6][C@H:7]([C:9]([OH:11])=[O:10])[NH2:8].[CH:16]1[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH:19]=[CH:18][C:17]=1[C:26](Cl)=[O:27]>>[NH2:1][C:2](=[N:12][N+:13]([O-:15])=[O:14])[NH:3][CH2:4][CH2:5][CH2:6][C@H:7]([C:9]([OH:11])=[O:10])[NH:8][C:26]([C:17]1[CH:18]=[CH:19][C:20]2[C:25](=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:16]=1)=[O:27]

Participants

3

Reactant 2

HCID 752462-Naphthoyl chlorideHCID 136333693HCID 136333693, compound

Product 1

HCID 136333692HCID 136333692, compoundYield 64%

Procedure

Prepared analogously to Example 4a) from (R)-N5 -[amino(nitroimino)methyl]-ornithine and 2-naphthoylchloride in a yield of 64% of theory. Colourless crystals which were used in the next step without further purification.

Workup

  1. customColourless crystals which were used in the next step without further purification

Sources & evidence

ORD record
ord-132ef3e7987746cd891c920ad8582488
Source dataset
uspto-grants-2000_09
Patent number
US06114390

Reaction notes

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