Ammonium Carbonate → HCID 53644843, compound

HRID 1953032Notes

Reaction equation

HRID 1953032 reaction equation
[CH3:1][C:2]([CH3:20])([O:4][C:5]([NH:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][C:17](O)=[O:18])=[CH:11][CH:10]=1)=[O:6])[CH3:3].C(=O)([O-])[O-].[NH4+:25].[NH4+]>>[CH3:1][C:2]([CH3:20])([O:4][C:5]([NH:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][C:17]([NH2:25])=[O:18])=[CH:11][CH:10]=1)=[O:6])[CH3:3]

Participants

3

Reactant 2

HCID 517111Ammonium CarbonateHCID 222827343-(4-{[(tert-Butoxycarbonyl)amino]methyl}phenyl)propanoic acid

Product 1

HCID 53644843HCID 53644843, compoundYield 84%

Procedure

Prepared analogously to Example 63a) from 4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]benzene propanoic acid, N,N'-carbonyldiimidazole and ammonium carbonate in a yield of 84% of theory. Colourless crystals, which were used in the following step without purification.

Workup

  1. customColourless crystals, which were used in the following step without purification

Sources & evidence

ORD record
ord-55d8892824e64157a1257d23216891b7
Source dataset
uspto-grants-2000_09
Patent number
US06114390

Reaction notes

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