HCID 53703543, compound → HCID 23302788, compound

HRID 1953250Notes

Reaction equation

HRID 1953250 reaction equation
[CH3:1][N:2]([CH3:38])[CH2:3][CH2:4][N:5]([S:25]([C:28]1[CH:29]=[CH:30][CH:31]=[C:32]2[C:37]=1[N:36]=[CH:35][CH:34]=[CH:33]2)(=[O:27])=[O:26])[C:6]1[CH:24]=[CH:23][C:9]2[N:10]([CH3:22])[C:11]([CH2:13][C:14]3[CH:21]=[CH:20][C:17]([C:18]#[N:19])=[CH:16][CH:15]=3)=[N:12][C:8]=2[CH:7]=1.[ClH:39].C(=O)([O-])[O-].[NH4+:44].[NH4+]>C(O)C>[ClH:39].[ClH:39].[CH3:38][N:2]([CH3:1])[CH2:3][CH2:4][N:5]([S:25]([C:28]1[CH:29]=[CH:30][CH:31]=[C:32]2[C:37]=1[N:36]=[CH:35][CH:34]=[CH:33]2)(=[O:26])=[O:27])[C:6]1[CH:24]=[CH:23][C:9]2[N:10]([CH3:22])[C:11]([CH2:13][C:14]3[CH:15]=[CH:16][C:17]([C:18]([NH2:44])=[NH:19])=[CH:20][CH:21]=3)=[N:12][C:8]=2[CH:7]=1

Participants

4

Reactant 2

HCID 53703543HCID 53703543, compoundHCID 86755731HCID 86755731, compound

Product 1

HCID 23302788HCID 23302788, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 1e from 4-[(5-(N-(2-dimethylamino-ethyl)-quinolin-8-yl-sulphonylamino)-1-methyl-1H-benzimidazol-2-yl)-methyl]-benzonitrile and hydrochloric acid/ammonium carbonate in ethanol.

Sources & evidence

ORD record
ord-c15b972346d24dd8be74ab58b791e61c
Source dataset
uspto-grants-2000_09
Patent number
US06114532

Reaction notes

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