Methyl chloroformate → HCID 53715258, compound

HRID 1953253Notes

Reaction equation

HRID 1953253 reaction equation
Cl.[CH3:2][CH:3]([CH3:43])[CH2:4][O:5][C:6]([CH2:8][N:9]([S:30]([C:33]1[CH:34]=[CH:35][CH:36]=[C:37]2[C:42]=1[N:41]=[CH:40][CH:39]=[CH:38]2)(=[O:32])=[O:31])[C:10]1[CH:29]=[CH:28][C:13]2[N:14]([CH3:27])[C:15]([CH2:17][C:18]3[CH:26]=[CH:25][C:21]([C:22]([NH2:24])=[NH:23])=[CH:20][CH:19]=3)=[N:16][C:12]=2[CH:11]=1)=[O:7].Cl[C:45]([O:47][CH3:48])=[O:46]>CC(C)=O.O>[CH3:2][CH:3]([CH3:43])[CH2:4][O:5][C:6]([CH2:8][N:9]([S:30]([C:33]1[CH:34]=[CH:35][CH:36]=[C:37]2[C:42]=1[N:41]=[CH:40][CH:39]=[CH:38]2)(=[O:32])=[O:31])[C:10]1[CH:29]=[CH:28][C:13]2[N:14]([CH3:27])[C:15]([CH2:17][C:18]3[CH:19]=[CH:20][C:21]([C:22]([NH2:24])=[N:23][C:45]([O:47][CH3:48])=[O:46])=[CH:25][CH:26]=3)=[N:16][C:12]=2[CH:11]=1)=[O:7]

Participants

4

Reactant 2

HCID 6586Methyl chloroformateHCID 23302491HCID 23302491, compound

Product 1

HCID 53715258HCID 53715258, compound

Reagents, catalysts & solvents 1

HCID 18366337Propan-2-one--water (1/1)Solvent

Procedure

Prepared analogously to Example 97 from 4-[(5-(N-(2-methylpropyloxycarbonylmethyl)-quinolin-8-yl-sulphonylamino)-1-methyl-1H-benzimidazol-2-yl)-methyl]-benzamidine-hydrochloride and methyl chloroformate in acetone/water.

Sources & evidence

ORD record
ord-6243fd945e08423b8aca899914999122
Source dataset
uspto-grants-2000_09
Patent number
US06114532

Reaction notes

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