Sodium Hydroxide → HCID 54166401, compound

HRID 1953255Notes

Reaction equation

HRID 1953255 reaction equation
Cl.C([O:4][C:5]([CH2:7][N:8]([S:34]([C:37]1[CH:38]=[CH:39][CH:40]=[C:41]2[C:46]=1[N:45]=[CH:44][CH:43]=[CH:42]2)(=[O:36])=[O:35])[C:9]1[CH:33]=[CH:32][C:12]2[N:13]([CH3:31])[C:14]([CH2:16][C:17]3[CH:30]=[CH:29][C:20]([C:21]([NH2:28])=[N:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])=[CH:19][CH:18]=3)=[N:15][C:11]=2[CH:10]=1)=[O:6])C.[OH-].[Na+]>C(O)C.O>[C:5]([CH2:7][N:8]([S:34]([C:37]1[CH:38]=[CH:39][CH:40]=[C:41]2[C:46]=1[N:45]=[CH:44][CH:43]=[CH:42]2)(=[O:36])=[O:35])[C:9]1[CH:33]=[CH:32][C:12]2[N:13]([CH3:31])[C:14]([CH2:16][C:17]3[CH:18]=[CH:19][C:20]([C:21]([NH2:28])=[N:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])=[CH:29][CH:30]=3)=[N:15][C:11]=2[CH:10]=1)([OH:6])=[O:4]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 70255846HCID 70255846, compound

Product 1

HCID 54166401HCID 54166401, compound

Reagents, catalysts & solvents 1

HCID 19096565Water ethanolSolvent

Procedure

Prepared analogously to Example 13 from 4-[(5-(N-ethoxycarbonylmethyl-quinolin-8-yl-sulphonylamino)-1-methyl-1H-benzimidazol-2-yl)-methyl]-N'-ethyloxycarbonyl-benzamidine-hydrochloride and sodium hydroxide in ethanol/water.

Sources & evidence

ORD record
ord-5759c2cbfbba4aafab4f5018de0f22f4
Source dataset
uspto-grants-2000_09
Patent number
US06114532

Reaction notes

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