HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → ST50554379
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Fluoro-3-nitroaniline | HCID 67768 | — |
| Reactant | Cyclohexanecarbonyl chloride | HCID 75938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | ST50554379 | HCID 3598338 | — |
Reaction Steps
15.6 g (0.1 mol) of 4-fluoro-3-nitro-aniline and 17.9 g (0.11 mol) of cyclohexylcarboxylic acid chloride are dissolved in 250 ml tetrahydrofuran and after the addition of 12.1 g (0.12 mol) of triethylamine the mixture is stirred for 3 hours at ambient temperature. The solvent is distilled off, the residue is mixed with water and extracted with ethyl acetate. The combined organic extracts are dried over sodium sulphate and concentrated by evaporation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06114532 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-3fbc48fa0f764eff9c6aee17b8bffac8 |
| Source note | uspto-grants-2000_09 |