Sodium Hydroxide → HCID 57246917, compound

HRID 1953262Notes

Reaction equation

HRID 1953262 reaction equation
C([O:3][C:4]([CH2:6][N:7]([S:35]([C:38]1[CH:39]=[CH:40][CH:41]=[C:42]2[C:47]=1[N:46]=[CH:45][CH:44]=[CH:43]2)(=[O:37])=[O:36])[C:8]1[CH:34]=[CH:33][C:11]2[N:12]([CH3:32])[C:13]([CH2:15][C:16]3[CH:31]=[CH:30][C:19]([C:20]([NH2:29])=[N:21][C:22]([O:24][C:25]([CH3:28])([CH3:27])[CH3:26])=[O:23])=[CH:18][CH:17]=3)=[N:14][C:10]=2[CH:9]=1)=[O:5])C.[OH-].[Na+]>C(O)C>[C:4]([CH2:6][N:7]([S:35]([C:38]1[CH:39]=[CH:40][CH:41]=[C:42]2[C:47]=1[N:46]=[CH:45][CH:44]=[CH:43]2)(=[O:37])=[O:36])[C:8]1[CH:34]=[CH:33][C:11]2[N:12]([CH3:32])[C:13]([CH2:15][C:16]3[CH:17]=[CH:18][C:19]([C:20]([NH2:29])=[N:21][C:22]([O:24][C:25]([CH3:27])([CH3:26])[CH3:28])=[O:23])=[CH:30][CH:31]=3)=[N:14][C:10]=2[CH:9]=1)([OH:5])=[O:3]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 57169230HCID 57169230, compound

Product 1

HCID 57246917HCID 57246917, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 13 from 4-[(5-(N-ethoxycarbonylmethylquinolin-8-yl-sulphonylamino)-1-methyl-1H-benzimidazol-2-yl)-methyl]-N'-tert.butyloxycarbonyl-benzamidine and sodium hydroxide in ethanol.

Sources & evidence

ORD record
ord-1788ff84d4c143198204bfab218122d9
Source dataset
uspto-grants-2000_09
Patent number
US06114532

Reaction notes

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