HCID 23302879, compound → HCID 23302298, compound

HRID 1953289Notes

Reaction equation

HRID 1953289 reaction equation
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][C:7]([N+:11]([O-])=O)=[CH:8][CH:9]=2)[CH:4]=[C:3]1[C:14]1[CH:21]=[CH:20][C:17]([C:18]#[N:19])=[C:16]([CH3:22])[CH:15]=1>[Pd].C(Cl)Cl.CO.[H][H]>[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][C:7]([NH2:11])=[CH:8][CH:9]=2)[CH:4]=[C:3]1[C:14]1[CH:21]=[CH:20][C:17]([C:18]#[N:19])=[C:16]([CH3:22])[CH:15]=1

Participants

5

Reactant 1

HCID 23302879HCID 23302879, compound

Product 1

HCID 23302298HCID 23302298, compound

Reagents, catalysts & solvents 3

HCID 23938PalladiumCatalystHCID 21226129Dichloromethane methanolSolventHCID 178418361HCID 178418361, compoundSolvent

Procedure

Prepared analogously to Example 1c from 4-(1-methyl-5-nitro-1H-indol-2-yl)-methyl-benzonitrile, palladium on activated charcoal in methylene chloride/methanol and hydrogen.

Sources & evidence

ORD record
ord-b7e4109d31294895acd6af75faa17af6
Source dataset
uspto-grants-2000_09
Patent number
US06114532

Reaction notes

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