Bromine → HCID 53696781, compound

HRID 1953294Notes

Reaction equation

HRID 1953294 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=[C:2]1[CH2:10][C:11]1[CH:18]=[CH:17][C:14]([C:15]#[N:16])=[CH:13][CH:12]=1.[Br:19]Br>C(Cl)Cl.C(Cl)(Cl)(Cl)Cl>[Br:19][C:3]1[C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=2[O:1][C:2]=1[CH2:10][C:11]1[CH:18]=[CH:17][C:14]([C:15]#[N:16])=[CH:13][CH:12]=1

Participants

5

Reactant 2

HCID 24408BromineHCID 23302816HCID 23302816, compound

Product 1

HCID 53696781HCID 53696781, compound

Reagents, catalysts & solvents 2

HCID 5943Carbon TetrachlorideSolventHCID 6344DichloromethaneSolvent

Conditions

Temperature
2 °C

Procedure

To a solution of 1.2 g (5 mmol) of 4-(benzofuran-2-yl)methyl-benzonitrile in 25 ml methylene chloride, a solution of 0.8 g (5 mmol) of bromine in 5 ml carbon tetrachloride is added dropwise at 2° C. The solution is stirred for 90 minutes at 2° C., the precipitate formed is suction filtered, washed with a little methylene chloride and dried.

Workup

  1. customthe precipitate formed
  2. filtrationfiltered
  3. washwashed with a little methylene chloride
  4. customdried

Sources & evidence

ORD record
ord-09094e685d5e4fd7b2afff0574ec8702
Source dataset
uspto-grants-2000_09
Patent number
US06114532

Reaction notes

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