HCID 23302657, compound → HCID 23302732, compound

HRID 1953297Notes

Reaction equation

HRID 1953297 reaction equation
[CH3:1][NH:2][C:3]1[CH:25]=[CH:24][C:6]([CH2:7][N:8]2[C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=3[N:10]=[C:9]2[CH2:17][CH2:18][C:19]([O:21][CH2:22][CH3:23])=[O:20])=[CH:5][C:4]=1[N+:26]([O-])=O>[Pd].CO.C(Cl)Cl>[NH2:26][C:4]1[CH:5]=[C:6]([CH:24]=[CH:25][C:3]=1[NH:2][CH3:1])[CH2:7][N:8]1[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=2[N:10]=[C:9]1[CH2:17][CH2:18][C:19]([O:21][CH2:22][CH3:23])=[O:20]

Participants

4

Reactant 1

HCID 23302657HCID 23302657, compound

Product 1

HCID 23302732HCID 23302732, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 21226129Dichloromethane methanolSolvent

Procedure

Prepared analogously to Example 1c from ethyl 3-[1-(4-methylamino-3-nitro-benzyl)-1H-benzimidazol-2-yl]-propionate and palladium on activated charcoal in methanol/methylene chloride.

Sources & evidence

ORD record
ord-3dc976007f964e59bd4177bc6ba2e0ab
Source dataset
uspto-grants-2000_09
Patent number
US06114532

Reaction notes

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