HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Alanine 1,1-dimethylethyl ester → (S)-2-(phenoxathiine-2-sulfonylamino)-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Alanine 1,1-dimethylethyl ester | HCID 89016 | — |
| Reactant | tert-Butyl L-valinate | HCID 114626 | — |
| Reactant | Thianthrene-2-sulfonyl chloride | HCID 15487617 | — |
| Reactant | Phenoxathiine-2-sulfonyl chloride | HCID 15487618 | — |
| Product | (S)-2-(phenoxathiine-2-sulfonylamino)-propionic acid | HCID 15487612 | — |
Reaction Steps
When in the procedure of Example 1, Step (b), thianthrene-2-sulfonyl chloride is replaced by phenoxathiine-2-sulfonyl chloride and (L)-valine-t-butyl ester is replaced with (L)-alanine-t-butyl ester, (S)-2-(phenoxathiine-2-sulfonylamino)-propionic acid is obtained as a white solid; mp 75-85° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06117869 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-fd4be9ba30f54c78ba0cc1427847e0b9 |
| Source note | uspto-grants-2000_09 |