HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl L-valinate → (S)-4-methanesulfinyl-2-(phenoxathiine-2-sulfonylamino)-butyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl L-valinate | HCID 114626 | — |
| Reactant | Tert-butyl (2S)-2-amino-4-(methylsulfanyl)butanoate | HCID 7010638 | — |
| Reactant | Thianthrene-2-sulfonyl chloride | HCID 15487617 | — |
| Reactant | Phenoxathiine-2-sulfonyl chloride | HCID 15487618 | — |
| Product | (S)-4-methanesulfinyl-2-(phenoxathiine-2-sulfonylamino)-butyric acid | HCID 15487613 | — |
Reaction Steps
When in the procedure of Example 1, Step (b), thianthrene-2-sulfonyl chloride is replaced by phenoxathiine-2-sulfonyl chloride and (L)-valine-t-butyl ester is replaced with (L)-methionine-t-butyl ester, (S)-4-methanesulfinyl-2-(phenoxathiine-2-sulfonylamino)-butyric acid is obtained as a white solid;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06117869 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-6bd0ad30024040d4bb9481e90c96e957 |
| Source note | uspto-grants-2000_09 |