HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 23298115, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | HCID 23298101 | HCID 23298101 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 23298115 | HCID 23298115 | 89.5% |
Reaction Steps
A mixture of 3-[(E)-2-(6-acetamido-3-pyridyl)vinyl]nitrobenzene (3.0 g), iron powder (1.48 g) and ammonium chloride (0.57 g), ethanol (30 ml) and water (9 ml) was stirred under reflux for 5 hours. The reaction was filtered, concentrated and extracted with chloroform. The extracts were chromatographed on silica gel (20 g, chloroform-methanol 100:1 as eluent) to give an oil. Crystallization from methanol afforded 3-[(E)-2-(6-acetamido-3-pyridyl)vinyl]aniline (2.4 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06117875 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-af891fd5e9ca4274ba1e12bd228268d9 |
| Source note | uspto-grants-2000_09 |