HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → 2-[3-(3-Aminophenyl)phenylamino]-3-nitropyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 2-[3-(3-Acetamidophenyl)phenylamino]-3-nitropyridine | HCID 22724420 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 2-[3-(3-Aminophenyl)phenylamino]-3-nitropyridine | HCID 23298139 | 108.4% |
Reaction Steps
A solution of 2-[3-(3-acetamidophenyl)phenylamino]-3-nitropyridine (10 g) in 3N hydrochloric acid (100 ml) was refluxed for 2 hours. The cold reaction was adjusted to pH 8 with saturated sodium bicarbonate solution and precipitated reddish crystals were collected, washed with water and dried to give 2-[3-(3-aminophenyl)phenylamino]-3-nitropyridine (9.53 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06117875 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-81168846e7234685b30b56206904f71f |
| Source note | uspto-grants-2000_09 |