HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → methyl (2RS,3S)-3-amino-2-hydroxyheptanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | phenylmethyl (2RS,3S)-3-amino-2-hydroxyheptanoate | HCID 56995658 | — |
| Product | methyl (2RS,3S)-3-amino-2-hydroxyheptanoate | HCID 54272153 | 91% |
Reaction Steps
The same reaction procedure for synthesizing of phenylmethyl (2RS,3S)-3-amino-2-hydroxyheptanoate as in Reference Example 17 was repeated except that benzyl bromide used in Reference Example 17 was replaced by 579 mg of methyl iodide, whereby 683 mg of the captioned methyl (2RS,3S)-3-amino-2-hydroxyheptanoate was obtained in a yield of 91%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06117870 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-c5f9c186745040cf8ede17d73f1edc76 |
| Source note | uspto-grants-2000_09 |