HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl 1-[N-(3,4-methylenedioxyphenylcarbonyl) amino]cyclohexanecarboxylate → 1-[N-(4-methoxybenzenesulfonyl)amino]cyclohexanecarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl 1-[N-(3,4-methylenedioxyphenylcarbonyl) amino]cyclohexanecarboxylate | HCID 23297898 | — |
| Reactant | phenylmethyl 1-[N-(4-methoxybenzenesulfonyl)amino]cyclohexanecarboxylate | HCID 23297905 | — |
| Product | 1-[N-(4-methoxybenzenesulfonyl)amino]cyclohexanecarboxylic acid | HCID 974157 | 57.4% |
Reaction Steps
Subsequently, the same procedure as in Reference Example 4 was repeated except that the ethyl 1-[N-(3,4-methylenedioxyphenylcarbonyl)amino]cyclohexanecarboxylate was replaced by 1.0 g (2.5 mmol) of phenylmethyl 1-[N-(4-methoxybenzenesulfonyl)amino]cyclohexanecarboxylate, whereby 450 mg of the captioned 1-[N-(4-methoxybenzenesulfonyl)amino]cyclohexanecarboxylic acid was obtained in a yield of 26%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06117870 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-1ee8674f153d4f5d9835038632c0034c |
| Source note | uspto-grants-2000_09 |