Phosphorus pentachloride → HCID 23298252, compound

HRID 1953458Notes

Reaction equation

HRID 1953458 reaction equation
P(Cl)(Cl)(Cl)(Cl)[Cl:2].[CH2:7]([O:9][C:10]([CH2:12][N:13]1[C:18]([CH3:19])=[CH:17][C:16]([S:20][CH2:21][CH2:22]O)=[C:15]([N+:24]([O-:26])=[O:25])[C:14]1=[O:27])=[O:11])[CH3:8]>C(Cl)Cl>[Cl:2][CH2:22][CH2:21][S:20][C:16]1[CH:17]=[C:18]([CH3:19])[N:13]([CH2:12][C:10]([O:9][CH2:7][CH3:8])=[O:11])[C:14](=[O:27])[C:15]=1[N+:24]([O-:26])=[O:25]

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 23298249HCID 23298249, compound

Product 1

HCID 23298252HCID 23298252, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

Phosphorus pentachloride (229 mg, 1.1 mmol) was added to a stirred solution of 1-ethyloxycarbonylmethyl-4-(2-hydroxyethylthio)-6-methyl-3-nitro-2-pyridinone (316 mg, 1.0 mmol) in methylene chloride (5 mL). After 15 min the reaction was diluted with methylene chloride and was washed with water, dried (Na2SO4) and evaporated to give the title compound as a yellow crystalline solid:

Workup

  1. washwas washed with water
  2. dry with materialdried (Na2SO4)
  3. customevaporated

Sources & evidence

ORD record
ord-469abdb495e24980b5e2cff7aaa31047
Source dataset
uspto-grants-2000_09
Patent number
US06117888

Reaction notes

Loading…