4-Hydroxybenzyl Alcohol → HCID 54080419, compound

HRID 1953469Notes

Reaction equation

HRID 1953469 reaction equation
Cl[CH2:2][C:3]1[N:7]([CH2:8][CH2:9][O:10][CH2:11][CH3:12])[C:6]2[CH:13]=[CH:14][CH:15]=[CH:16][C:5]=2[N:4]=1.[OH:17][C:18]1[CH:25]=[CH:24][C:21]([CH2:22][OH:23])=[CH:20][CH:19]=1>>[CH2:11]([O:10][CH2:9][CH2:8][N:7]1[C:6]2[CH:13]=[CH:14][CH:15]=[CH:16][C:5]=2[N:4]=[C:3]1[CH2:2][O:17][C:18]1[CH:25]=[CH:24][C:21]([CH2:22][OH:23])=[CH:20][CH:19]=1)[CH3:12]

Participants

3

Reactant 2

HCID 1254-Hydroxybenzyl AlcoholHCID 13656984HCID 13656984, compound

Product 1

HCID 54080419HCID 54080419, compoundYield 83.4%

Procedure

In a manner similar to that of Production Example 9, the title compound (yield: 83.4%) was obtained as pale yellow prisms by use of 2-chloromethyl-N-(2-ethoxyethyl)benzimidazole and 4-Hydroxybenzyl alcohol.

Sources & evidence

ORD record
ord-154fd7f7c9144bb7ab2058ed3f23e3e3
Source dataset
uspto-grants-2000_09
Patent number
US06117886

Reaction notes

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