HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride → 2-((Phenyl)carbonyl)amino-7-nitrotetralin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | 7-Nitro-1,2,3,4-tetrahydronaphthalen-2-amine | HCID 23298421 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Potassium Carbonate | HCID 11430 | — |
| Product | 2-((Phenyl)carbonyl)amino-7-nitrotetralin | HCID 23298409 | — |
Reaction Steps
To 2-amino-7-nitrotetralin (1.8 g, 9.39 mmol, derived from dibenzoyl-D-tartaric acid) in THF (50 ml) and 10% K2CO3 (100 ml) was added benzoyl chloride (1.2 ml, 10.1 mmol). After the addition was complete, the mixture was diluted with water to a volume of 250 ml. The precipatated solids were collected by filtration, washed with water and dried in vacuo: (2.8 g, 100%), m.p. 208-209° C., [a]D +21.9° (c 0.33 DMSO).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06117898 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-3b309b198dfe49dab9238aa2f9ea6f2d |
| Source note | uspto-grants-2000_09 |