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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1953613Generated: October 29, 2026

3-Thiophenacetic acid → N-[(3thienyl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/1953613

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Thiophenacetic acidHCID 23404—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3thienyl)acetyl]alanine Iso-butyl EsterHCID 53969374—

Reaction Steps

Following General Procedure I above, and using 3-thiopheneacetic acid (Aldrich) and alanine iso-butyl ester (prepared following General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06117901
Source datasetuspto-grants-2000_09
ORD IDord-c701b546d6d54ad6a7352047f23fcc18
Source noteuspto-grants-2000_09