Acetic Acid → HCID 10527264, compound

Participants

Reaction Steps

A procedure similar to that described in Example 12 was repeated, except that 0.9 g of 5-{4-(3-methyl-5 -phenylimidazo[5,4-b]pyridin-2-ylmethoxy)benzyl}-3-triphenylmethylthiazolidine-2,4-dione (prepared as described in Preparation 111) was treated with 36 ml of a 3:1 by volume mixture of acetic acid and water. After working up the product as described in Example 12, the resulting crude product was crystallized by trituration with ethyl acetate, to give 420 mg of the title compound, melting at 211-213° C.

Provenance & Evidence