HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-methyl-6-nitroaniline → 5-Bromo-3-methylbenzene-1,2-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-methyl-6-nitroaniline | HCID 522679 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-Bromo-3-methylbenzene-1,2-diamine | HCID 1516397 | — |
Reaction Steps
A solution of 15 g (64.9 mmol) of 4-bromo-2-methyl-6-nitroaniline in 300 ml of ethanol is hydrogenated at about 27° for 4 hours in the presence of 1.5 g of Raney nickel. The reaction mixture is then filtered and evaporated. The title compound is obtained as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06117873 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-22a9ac5967f64a94896b8ab22418fd80 |
| Source note | uspto-grants-2000_09 |