HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalic Acid → 7-Fluoro-5-methyl-1,2,3,4-tetrahydroquinoxaline-2,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalic Acid | HCID 971 | — |
| Reactant | HCID 23297976 | HCID 23297976 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Water | HCID 962 | — |
| Product | 7-Fluoro-5-methyl-1,2,3,4-tetrahydroquinoxaline-2,3-dione | HCID 23298003 | — |
Reaction Steps
20 g (0.118 mol) of 2,3-diamino-5-fluorotoluene and 15.8 g (0.176 mol) of oxalic acid are stirred at reflux for 16 hours in 4N hydrochloric acid. The reaction mixture is cooled, diluted with water, filtered off on a suction filter and washed with water. The title compound is obtained as beige crystals of m.p.>300° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06117873 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-1fbbc6035fac439cbe359fc4f3f6efb6 |
| Source note | uspto-grants-2000_09 |