HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1953775Generated: November 2, 2026
Sulfuric Acid → 5-Bromomethyl-7-nitro-2,3-dimethoxyquinoxaline
https://huagongshe.com/reaction/1953775
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Isopropyl nitrate | HCID 15575 | — |
| Reactant | 5-Bromomethyl-2,3-dimethoxy-quinoxaline | HCID 15941729 | — |
| Product | 5-Bromomethyl-7-nitro-2,3-dimethoxyquinoxaline | HCID 23297983 | — |
Reaction Steps
25 ml of sulfuric acid are cooled to 0° C. and 9.5 g (33.55 mmol) of 5-bromomethyl-2,3-dimethoxyquinoxaline are then added. After a further 10 minutes, 3.39 ml (1 eq.) of isopropyl nitrate are added and the mixture is stirred at 0° C. for 1 hour. The mixture is poured onto ice, and the solid is filtered off and washed with water. The title compound is obtained as a beige solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06117873 |
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| Source dataset | uspto-grants-2000_09 |
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| ORD ID | ord-09c7b5fa0f974ed68a0b22b52b3325fd |
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| Source note | uspto-grants-2000_09 |
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