HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[3-(Trifluoromethyl)phenyl]-1,2,3,6-tetrahydropyridine → Xaliproden hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[3-(Trifluoromethyl)phenyl]-1,2,3,6-tetrahydropyridine | HCID 11128034 | — |
| Reactant | HCID 12698954 | HCID 12698954 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Xaliproden hydrochloride | HCID 128918 | — |
Reaction Steps
It has also been found that the reaction of 2-(2-chloroethyl)naphthalene with 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine under the conditions described in EP 0 101 381, i.e. in ethanol under reflux for 20-24 hours, gives 1-[2-(2-naphthyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride with very low yields.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06118006 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-fba1f7164c484c67b50e637c5654cdf7 |
| Source note | uspto-grants-2000_09 |