1-Acetoxy-2-bromoethane → HCID 76489103, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of [S-(R*,R*)]-4-methyl-2-methylamino-pentanoic acid [2-(4-benzyloxy-phenyl)-1-tert-butylcarbamoyl-ethyl]-amide (0.55 mmol), diisopropyl ethylamine (1.65 mmol), 2-bromoethyl acetate (0.8 mmol), and anhydrous THF (6 mL) was stirred at 25° C. for 6 hours. The precipitate was filtered off. The reaction mixture was concentrated and purified by column chromatography on silica gel eluting with 10% acetone/methylene chloride to give the titled compound (84% yield).

Provenance & Evidence