反应详情

C 18 resin: Pentadecanoyl chloride was synthesized by reacting 10 ml of 2 M thionyl chloride in 10 ml of toluene with 1.5 gm pentadecanoic acid. After 40 minutes of refluxing, the remaining thionyl chloride and toluene were removed by distillation. 4 gm of the 3-amino-propyl resin was then incubated overnight with the freshly prepared pentadecanoyl chloride in pyridine. The next day, the resin was twice washed with methylene chloride and then three times more with methanol and dried.

1. temperatureAfter 40 minutes of refluxing
2. customthe remaining thionyl chloride and toluene were removed by distillation
3. washThe next day, the resin was twice washed with methylene chloride
4. dry with materialthree times more with methanol and dried