HCID 86756116, compound → HCID 131721995, compound

HRID 1953972Notes

Reaction equation

HRID 1953972 reaction equation
C[O:2][C:3](=[O:37])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]1[C:16](=[CH:18][CH:19]=[C:20]([OH:36])[C:21]=1[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][C:33]([OH:35])=[O:34])[OH:17].C(O)C.[OH-].[Na+:42].O>>[Na+:42].[C:20]1([C:21]([CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][C:33]([O-:35])=[O:34])=[C:15]([CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([O-:37])=[O:2])[C:16](=[CH:18][CH:19]=1)[OH:17])[OH:36].[Na+:42]

Participants

3

Reactant 2

HCID 86756116HCID 86756116, compoundHCID 131721353HCID 131721353, compound

Product 1

HCID 131721995HCID 131721995, compound

Procedure

Hydroquinone bislauric acid methyl ester prepared in Example 1 (2.8 g) was stirred in sodium hydroxide ethanol/water solution at room temperature for 12 hours. At first, the solution was cloudy. By the end of the reaction, the solution was clear. The crude product was extracted with n-butanol twice. After the solvent was rotevaporated, the remaining material was washed with ethanol. The white solid material was collected by filtration. NMR results showed that the material is the desired product. ##STR23##

Workup

  1. customBy the end of the reaction
  2. extractionThe crude product was extracted with n-butanol twice
  3. washthe remaining material was washed with ethanol
  4. filtrationThe white solid material was collected by filtration
  5. customNMR results

Sources & evidence

ORD record
ord-66b627ddcd354ddab74d97c1d3c8dfd8
Source dataset
uspto-grants-2000_09
Patent number
US06121222

Reaction notes

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