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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1954014Generated: October 30, 2026

Potassium Carbonate → HCID 178505549, compound

https://huagongshe.com/reaction/1954014

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactantp-Chlorophenacyl bromideHCID 68303—
Reactant4-FluorobenzamidineHCID 4295238—
SolventChloroformHCID 6212—
ProductHCID 178505549HCID 178505549—

Reaction Steps

To a two-phase mixture of 30% K2CO3 solution (5 ml) and chloroform (5 mL) containing 276 mg of 4-fluorobenzamidine was added a solution of 468 mg of 2-bromo-4'-chloroacetophenone in chloroform (3 mL). After stirring for 1 hr, the reaction mixture was filtered. The white crystallinesolid was washed with distilled water and dried in a vacuum oven overnight to afford 2-(4-fluorophenyl)4-(4-chlorophenyl)imidazole (Compound 1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06121260
Source datasetuspto-grants-2000_09
ORD IDord-48bb087bcd0b4f4ea42f7eb7d7388d78
Source noteuspto-grants-2000_09