Lithium tri-n-butoxyaluminum hydride → HCID 131722002, compound

Participants

Reaction Conditions

Reaction Steps

Lithium tri-n-butoxyaluminum hydride (0.2 mL, 1M in THF) was slowly added to a stirred solution of the product from Example 15 (0.058 g) in 1 mL of anhydrous THF at -70° C. under a nitrogen atmosphere. After stirring at -70° C. for 3 hours, the mixture was partitioned between 50 mL of ether and 10 mL of 1N-HCl. The etheral solution was washed with brine, dried over magnesium sulfate anhydrous. The obtained crude product was purified by preparative TLC, using 35% acetone in hexane as a solvent to afford 0.025 g of the title compound.

Provenance & Evidence