HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 5-[(3,4-Dihydroxy-5-nitrophenyl)methylidene]-3-methyl-2-thioxothiazolidin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 4-Thiazolidinone, 3-methyl-2-thioxo- | HCID 72900 | — |
| Reactant | 3,4-Dihydroxy-5-nitrobenzaldehyde | HCID 5748957 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 5-[(3,4-Dihydroxy-5-nitrophenyl)methylidene]-3-methyl-2-thioxothiazolidin-4-one | HCID 53867513 | — |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
A solution containing 0.74 g (0.005 mol) of 3-methyl-2-thioxothiazolidin-4-one, 0.92 g (0.005 mol) of 3,4-dihydroxy-5-nitrobenzaldehyde, 0.05 ml of piperidine in 10 ml of acetic acid was heated for 8 h at 100° C. The product was filtered and washed with 2-propanol. Yield 0.87 g (56%), mp 274-276° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06121303 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-fbf74dad933e4f159c3e9b7e6cbddfe8 |
| Source note | uspto-grants-2000_09 |