HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 4-[(3,4-Dihydroxy-5-cyanophenyl)methylidene]-2-thioxoimidazolidin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 2-Thiohydantoin | HCID 1274030 | — |
| Reactant | 5-Formyl-2,3-dihydroxybenzonitrile | HCID 15292583 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 4-[(3,4-Dihydroxy-5-cyanophenyl)methylidene]-2-thioxoimidazolidin-5-one | HCID 54390461 | — |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
A solution containing 0.58 g of thiohydantoin, 0.82 g of 3,4-dihydroxy-5-cyanobenzaldehyde and 0.1 ml of piperidine in 10 ml of acetic acid was heated for 4 h at 100° C. The product was filtered and washed with ether. Yield 0.51 g, mp 210-213° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06121303 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-ccfd56c7a2ba40ce8bc9e8cbcded8eaf |
| Source note | uspto-grants-2000_09 |